Claudin18.2/Miapaca2
CBP74142
詢(xún) 價(jià)
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產(chǎn)品描述
產(chǎn)品數據庫
| I. Background | |
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Claudin18是位于細胞膜表面緊密連接的主要成分，它在維持細胞極性和屏障功能以及促進(jìn)耐酸能力方面起著(zhù)重要作用。CLDN18的第一個(gè)外顯子可以選擇性剪接，形成兩個(gè)具有高度同源氨基酸序列的不同剪接突變體(CLDN18.1和CLDN18.2)?？缒さ鞍證LDN18由兩個(gè)細胞外環(huán)、四個(gè)跨膜結構域和一個(gè)細胞質(zhì)結構域組成。 |
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II. Introduction |
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| Host Cell: |
Miapaca2 |
| Expressed gene: |
Claudin18.2 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: |
DMEM+10%FBS+5%馬血清+2ug/ml puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| III. Description of Host Cell Line | |
| Species: | Homo sapiens, human |
| Tissue： | pancreas |
| Disease: | carcinoma |
| Morphology: | attached epithelial with floating rounded cells |
| Growth Mode: | attached epithelial with floating rounded cells |
| IV. Representative Data | |
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1. Claudin18.2/Miapaca2 |
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